(A and B) WB on BMDM of indicated genotypes 6 hr (A) and 3 hr (B), and IFN-I production 20 hr post indicated stimuli. WB probed for proteins indicated on left of panels. Bar graphs show quantification of indicated WB signals. IFN-I levels measured as in Figure 1A. Error bars, mean ± s.e.m. *P≤0.05, **P≤0.01, ***P≤0.001, ****P≤0.0001, NS = non-significant, Student’s t-test, combining results from 3 independent experiments.