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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Cytoskeleton (Hoboken). 2017 Sep 30;74(11):426–442. doi: 10.1002/cm.21410

Figure 10. Lack of a deeper component of dense bodies changes their shape from “dot” like to “zipper” like.

Figure 10

(A) Wild type, atn-1 (ok84), and unc-98 (sf19) worms were immunostained with antibodies against UNC-95, UNC-112, PAT-6, and UNC-89. Anti-UNC-95, anti-UNC-112, and anti-PAT-6, localize to dense bodies and M-lines. Anti-UNC-89, localize only to M-lines. Images were captured by SIM. In the atn-1 (ok84) mutant, the dense bodies all appear like the “zipper” like structures normally found at muscle cell boundaries (compare with Figure 5). In contrast, in the unc-98(sf19) mutant, dense bodies mostly appear normal. Black scale bar represents 10 µm. (B) Enlargement of UNC-95 localization at a wild type cell boundary (left) and at an atn-1(ok84) dense body (right). Note the similarity in these two structures. Scale bar, 1 µm.