Figure 3.

(A) Family tree and C-terminal sequence of AIP showing amino acids from codon 327 and (B) nucleotides from c.981 based on NM_003977 coding cDNA. The stop codon TGA (*) is mutated to CGA, which is coding for arginine (R). No stop codons are present in the rest of the RNA. Germline (C) and tumor (D) DNA sequence of the proband, showing reduced height for ‘T’ (normal sequence) allele. The lack of complete absence of the T allele corresponds to the pathological report suggesting some normal tissue in the sample.