Table 1.
Indication for DBS | Onset of seizures | Semiology | Inter ictal EEG | Ictal EEG | Stimulation parameters at onset of seizures | Fate of DBS | |
---|---|---|---|---|---|---|---|
Patient 1 | Poststroke pain (Haemorrhagic stroke on the right) | 12 months |
Affective seizure (Psychic aura) and Speech arrest Brought on by rapid ramping of stimulation |
Intermittent, infrequent sharp transients over the frontocentral regions. | Symmetrical frontal delta wave activity in long runs |
3.5 mA 130 Hz 450 mics |
Discontinued but felt to be worthwhile even at low settings |
Patient 2 | Poststroke pain (Right side stroke) |
24 months 2 GTC seizure with suprathrehold stimulation in immediate postoperative period. |
Loss of awareness with lip smacking (Automotor seizures) Two generalized tonic clonic seizures reported |
Fast activity is prominent over the vertex | No electrographic change |
8 mA 130 Hz 450 mics |
Discontinued |
Patient 3 | Postsurgical pain on the right following Spinal surgery for syringomyeila | 12 months |
Left arm tonic seizures with speech arrest Minor jerks in the left leg sometimes (Left leg myoclonic seizures) |
Sharp transients are noted intermittently, maximal over both frontal regions, and occasionally focal in the right superior frontal area | No electrographic change |
6 mA 130 Hz 450 mics |
Discontinued, then resumed (patient request) Following management of seizures. Discontinued again following seizure recurrence |
Patient 4 | Whole spine pain‐failed back surgery | 20 months |
Dialeptic (Behavioural arrest with loss of awareness) seizures with secondary generalization (generalized seizures are nocturnal) |
Sharp wave discharges are seen across the fronto‐central mid‐line with right sided emphasis | Rhythmical, symmetrical 6 Hz theta slow wave activity across the fronto‐central regions that increments in amplitude and slows in frequency before ending abruptly |
5V 130 Hz 450 mics |
Discontinued, then resumed (patient request) Following management of seizures. PC&S device (see later in text) implanted. |