Table 3.
Summary of the Most Important Effects Shown in Quantitative Bone Marrow MRI Studies in Multiple Myeloma
| Effect | Study | Subjects | MRI/MRS technique |
|---|---|---|---|
| Diffusion | |||
| ADC ↑ in treatment responders | Horger et al, 2011 | 12 patients | Single‐shot DW EPI (1.5T) |
| ADC ↑ in tumors compared to yellow and red marrow | Padhani et al, 2013 | 39 patients | Single‐shot DW EPI (1.5T) |
| Negative correlation between change in ADC and change in laboratory markers of treatment response | Giles et al, 2014 | 34 patients | Single‐shot DW EPI (1.5T) |
| Perfusion | |||
| Time intensity curve parameters can differentiate between different MM groups | Dutoit et al, 2013 | 219 patients | DCE‐MRI (1.5T) |