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. 2017 Aug 26;33(1):88–98. doi: 10.1002/mds.27105

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© 2017 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Overviews of genomic reconstructions of two novel microbial populations depleted in patients with PD. (A) OTU_171, classified as Melainabacterium, (B) OTU_469, classified as alpha‐proteobacterium. 1) Contiguous sequences with lengths, 2) metagenomic depth of coverage, 3) % similarity to MelB1,57 4 and 5) predicted proteins colored according to functional categories, 6 and 7) tRNA and rRNA loci, and E) endoglucanase with synuclein‐like domain; pink spokes highlight unique essential genes, golden spokes highlight phylogenetic marker genes. kb = kilobase; tRNA, transfer RNA.