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. 2018 Feb 13;6:34. doi: 10.1186/s40168-018-0419-2

Fig. 1.

Fig. 1

Variations of ARG subtypes in different samples over the course of chlortetracycline administration. a Principal component analysis of ARG subtypes. b Heatmap of variations of ARG subtypes based on the relative abundance of ARG subtypes. Significant (P < 0.05) increases and decreases are shown by border lines of cells colored by red and black, respectively. ARG subtypes with an average abundance > 1% are shown. See Additional file 2: Table S4 for the relative abundances of ARG subtypes