Fig. 5.

NGS library construction with alternatively sheared gDNA by using SALP method. a Schematic of library construction with the enzymatically digested and sonicated DNA by using SALP method. b Distribution of reads density of NGS library constructed with the Hind III-digested HepG2 gDNA and the density of predicted Hind III restriction sites in whole genome. c Distribution of reads density of NGS library constructed with the sonicated HepG2 gDNA. The information of other chromosomes was shown as Additional file 10: Figure S6 and Additional file 11: Figure S7