Fig. 5.

Real-time PCR detected the difference expression and diagnostic value of RRS1 for thyroid carcinoma in children and adults. a Expression of RRS1 in PTC (mean = 1.51, n = 24) is higher than that in pericarcinous tissues (mean = 0.54, n = 14, unpaired t-test, P < 0.01). b Real-time PCR detects RRS1 expression in 12 paired carcinoma and pericarcinous tissues (paired t-test, P < 0.01). c Pearson correlation coefficient measures the relationship between RRS1 expression and age in PTC tumors (R = 0.2638). d Receiver operating characteristic (ROC) curve of 22 PTC tissues and 12 pericarcinous tissues (AUC is 0.850, P < 0.0001). *P value < 0.1, **P value < 0.01, ***P value < 0.001