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. 2018 Feb 13;10:20. doi: 10.1186/s13148-018-0448-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — CpG methylation analysis. a Percentage of 5′-methylcytosine content in genomic DNA in patients with HIV versus non-HIV infected individuals. Horizontal bars represent mean values and boxes IQR; (b) correlation plot between global DNA methylation and CD4+/CD8+ T cell ratio (Pearson correlation test); and (c) correlation plot between global DNA methylation and DNMT1 expression in the group of HIV-1 controllers (due to the nature of variables, the nonparametric Spearman correlation test was used)