Table 3.

Frequency of individuals showing upregulation in all three genes forming the SETDB1-DNMT3a-HDAC1 complex, which interacts with Tat

Type of patient		SEDTB1 + DNMT3A + HDAC1 complex
		Upregulated	p value
HIV negative (n = 32)		5 (16%)	< 0.001
HIV positive	Noncontroller (n = 26)	8 (31%)
	cART recipient (n = 25)	19 (76%)
	HIV-controller(n = 34)	11(32%)

Due to missing values, only patients with expression values for SEDTB1, DNMT3A, and HDAC1 were included in this analysis (n = 117). P value indicates differences between the cART recipients compared to the other subgroups