Table 2.

Synergistic activity of FC04–100 with the combination cefalexin:kanamycin

	MIC (μg/mL)
Species and strains	CEF	KAN	CEF:KANa	CEF:KAN (+FC)b	Foldc
S. aureus MRSA USA100 ATCC BAA-41	256	256	128:86	4:3	32
S. aureus MRSA USA300 ATCC BAA-1556	256	> 1024	256:171	8:6	32
S. aureus MRSA COL	256	4	4:3	0.5:0.35	8

Abbreviations: CEF cefalexin, KAN kanamycin, FC FC04–100

^aCEF:KAN was used at a proportion of 3:2

^bFC04–100 was used at a sub-MIC of 4 μg/mL

^cThe fold increase in susceptibility is the ratio of the MIC of CEF:KAN alone vs CEF:KAN in the presence of FC04–100