Table 1.
Significantly associated variants in the GWA studies based on MLMs
| refSNP_ID | BTA | PVL | WBC | Position c | ||||
|---|---|---|---|---|---|---|---|---|
| b a | SD | p b | b a | SD | p b | |||
| rs110155623 | 23 | −0.5 | 0.10 | 7.20 × 10 − 07 | −0.44 | 0.09 | 6.23 × 10 − 07 | 20,692,320 |
| rs41587216 | 23 | −0.15 | 0.03 | 5.06 × 10 − 07 | −0.13 | 0.03 | 4.95 × 10 − 07 | 22,300,959 |
| rs41566363 | 23 | −0.18 | 0.03 | 1.97 × 10 − 07 | −0.15 | 0.03 | 5.53 × 10 − 07 | 22,997,898 |
| rs41641297 | 23 | 0.21 | 0.03 | 2.80 × 10 −10 | 0.15 | 0.03 | 5.19 × 10 − 08 | 24,181,053 |
| rs109343703 | 23 | 0.24 | 0.04 | 1.95 × 10 − 08 | – | – | – | 24,699,202 |
| rs110499907 | 23 | 0.21 | 0.04 | 1.96 × 10 − 07 | – | – | – | 24,727,613 |
| rs110473048 | 23 | 0.21 | 0.03 | 1.78 × 10 −12 | 0.14 | 0.03 | 9.97 × 10 −08 | 25,109,188 |
| rs110525467 | 23 | −0.36 | 0.04 | 5.32 × 10 −16 | −0.24 | 0.04 | 5.90 × 10 −10 | 25,426,985 |
| rs110579760 | 23 | 0.25 | 0.04 | 3.66 × 10 −09 | – | – | – | 25,507,676 |
| rs110836188 | 23 | 0.23 | 0.04 | 6.50 × 10 −11 | – | – | – | 27,088,825 |
| rs41255514 | 23 | 0.23 | 0.03 | 1.47 × 10 −11 | – | – | – | 27,305,227 |
| rs17872223 | 23 | 0.22 | 0.03 | 6.99 × 10 −12 | – | – | – | 27,306,795 |
| rs110861313 | 23 | 0.19 | 0.03 | 7.02 × 10 −11 | 0.12 | 0.02 | 5.70 × 10 −07 | 27,444,064 |
| rs17871874 | 23 | 0.17 | 0.03 | 2.69 × 10 −07 | 0.15 | 0.03 | 1.96 × 10 − 07 | 27,485,467 |
| rs110260956 | 23 | 0.21 | 0.04 | 7.70 × 10 −07 | – | – | – | 27,545,231 |
| rs110350951 | 23 | 0.14 | 0.03 | 1.54 × 10 −07 | – | – | – | 27,841,983 |
| rs110794231 | 23 | −0.16 | 0.03 | 6.44 × 10 − 09 | – | – | – | 27,887,914 |
| rs41587536 | 23 | −0.15 | 0.03 | 2.25 × 10 − 08 | – | – | – | 27,923,154 |
| rs110742604 | 23 | −0.26 | 0.03 | 6.67 × 10 −14 | −0.16 | 0.03 | 8.18 × 10 − 08 | 28,087,630 |
| rs109856572 | 23 | −0.18 | 0.03 | 1.27 × 10 − 08 | −0.14 | 0.03 | 1.72 × 10 − 07 | 28,649,349 |
| rs110769723 | 23 | −0.25 | 0.04 | 3.01 × 10 − 08 | – | – | – | 29,285,952 |
| rs109015676 | 23 | −0.21 | 0.04 | 4.82 × 10 − 07 | – | – | – | 29,535,762 |
| rs110034224 | 23 | −0.18 | 0.04 | 5.46 × 10 − 07 | – | – | – | 30,662,593 |
| rs110277740 | 23 | – | – | – | −0.19 | 0.03 | 2.20 × 10 − 08 | 31,286,064 |
| rs109754326 | 23 | −0.15 | 0.03 | 2.99 × 10 − 07 | – | – | – | 33,296,630 |
Abbreviations: refSNP_ID: SNP Identification based on dbSNP (http://www.ncbi.nlm.nih.gov/SNP/), PVL: proviral load, WBC: whole blood cells counts, SD: standard deviation
aSNP effect size (β of regression)
bp-value: Under null hypothesis, probability of obtaining the observed effect size
cSNP location according to bovine genome assembly UMD3.1