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. Author manuscript; available in PMC: 2018 Feb 14.
Published in final edited form as: Toxicol Appl Pharmacol. 2017 Jul 1;330:1–8. doi: 10.1016/j.taap.2017.06.023

Fig. 4.

Fig. 4

Deficiency of FGF15 attenuates both basal and HFD induced liver fibrosis. (A) Liver sections were stained with Sirius Red (image taken at 4×) and (B) the relative area of the liver stained was quantified. (C) The relative mRNA expression of Collagen 1α1 and Timp1 was decreased in HFD fed Fgf15/ mice compared to WT mice while expression of Tgfβ1 and Ctgf was not altered. There was a trend for decreased αSMA in HFD-fed KO mice compared to WT mice. *Statistical significance between diets; #Statistical significance between WT and KO mice on corresponding diets (p ≤ 0.05).