Figure 3. Pup retrieval is impaired in lactating ephrin-A5^-/- mice.

The latencies to retrieve the 1^st and 3^rd pup on postnatal day 4 (a) and 6 (b) were tested in ephrin-A5^-/- (n=9 per test day), heterozygous (n=10) and wild-type (n=8) lactating female mice. There were significant differences between the genotypes on both test days where the mutant females took longer to retrieve their pups than both the wild-type and the heterozygous mice. Data are presented as mean latency to retrieve the x pup +SEM. (c) The percentage of females that retrieve their pups were significantly lower in ephrin-A5^-/- mice compared to wild-type and heterozygous control females. (d) No differences were observed across the days tested. Data are presented as mean latency to retrieve the 1^st pup ±SEM. * indicates significantly different from wild-type mice; p<0.05. ** indicates significantly different from heterozygous mice; p<0.05.