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. 2018 Feb 5;2(3):263–270. doi: 10.1182/bloodadvances.2017012005

Table 2.

Anti-HLA antibodies in patients who underwent haplo-HCT

Number Graft type Anti-HLA antibodies Donor-specific anti-HLA antibodies Outcome
Class I Class II Class I Class II
1 CD34+ selected* No No No No Stable
2 CD34+ selected No No No No Rejection
3 CD34+ selected No No No No Rejection
4 CD34+ selected No No No No Stable
5 CD34+ selected No Yes No No Rejection
6 CD34+ selected No Yes No No Stable
7 CD34+ selected No No No No Stable
8 CD34+ selected Yes Yes A24; MFI = 21 520 No Rejection
9 CD34+ selected Yes No B57; MFI = 777 No Rejection
10 CD34+ selected No No No No Stable
11 CD34+ selected No No No No Rejection
12 CD34+ selected No No No No Stable
13 CD34+ selected Yes Yes A23; MFI=16891 DQ2; MFI = 2358 Rejection
B45; MFI = 21 993
14 TCRαβ depleted No No No No Stable
15 TCRαβ depleted Yes Yes No No Rejection
16 TCRαβ depleted No No No No Stable
17 TCRαβ depleted No No No No Stable
18 TCRαβ depleted No No No No Stable

“No” indicates that antibodies were not found.

MFI, mean fluorescence intensity.

*

CD34+-selected and/or CD3+/19+-depleted grafts.

TCRαβ+/CD19+-depleted grafts.