Table 2.
Number | Graft type | Anti-HLA antibodies | Donor-specific anti-HLA antibodies | Outcome | ||
---|---|---|---|---|---|---|
Class I | Class II | Class I | Class II | |||
1 | CD34+ selected* | No | No | No | No | Stable |
2 | CD34+ selected | No | No | No | No | Rejection |
3 | CD34+ selected | No | No | No | No | Rejection |
4 | CD34+ selected | No | No | No | No | Stable |
5 | CD34+ selected | No | Yes | No | No | Rejection |
6 | CD34+ selected | No | Yes | No | No | Stable |
7 | CD34+ selected | No | No | No | No | Stable |
8 | CD34+ selected | Yes | Yes | A24; MFI = 21 520 | No | Rejection |
9 | CD34+ selected | Yes | No | B57; MFI = 777 | No | Rejection |
10 | CD34+ selected | No | No | No | No | Stable |
11 | CD34+ selected | No | No | No | No | Rejection |
12 | CD34+ selected | No | No | No | No | Stable |
13 | CD34+ selected | Yes | Yes | A23; MFI=16891 | DQ2; MFI = 2358 | Rejection |
B45; MFI = 21 993 | ||||||
14 | TCRαβ depleted† | No | No | No | No | Stable |
15 | TCRαβ depleted | Yes | Yes | No | No | Rejection |
16 | TCRαβ depleted | No | No | No | No | Stable |
17 | TCRαβ depleted | No | No | No | No | Stable |
18 | TCRαβ depleted | No | No | No | No | Stable |
“No” indicates that antibodies were not found.
MFI, mean fluorescence intensity.
CD34+-selected and/or CD3+/19+-depleted grafts.
TCRαβ+/CD19+-depleted grafts.