Graft failure. (A) Graft failure by recipient age and donor-recipient relationship. Two-year cumulative incidence of graft failure adjusted for disease among recipients younger than 55 years was 17% (95% CI, 11%-26%) for parent donors, 6% (95% CI, 4%-10%) for sibling donors, and 7% (95% CI, 3%-13%) for offspring donors, and among recipients at least 55 years old, it was 13% (95% CI, 7%-20%) for sibling donors and 11% (95% CI, 8%-15%) for offspring donors. (B) Graft failure by recipient age and donor age. The 2-year cumulative incidence of graft failure adjusted for disease among recipients younger than 55 years was 7% (95% CI, 4%-12%) with donors younger than 30 years and 8% (95% CI, 5%-13%) with donors at least 30 years old, and among recipients at least 55 years old, it was 17% (95% CI, 9%-26%) with donors younger than 30 years and 13% (95% CI, 8%-18%) with donors at least 30 years old.