Table 2.

Effect of patient age, donor-recipient relationship, and donor age on overall mortality, nonrelapse mortality, and relapse

	Overall mortality, hazard ratio (95% CI)*	Nonrelapse mortality, hazard ratio (95% CI)†	Relapse, hazard ratio (95% CI)‡
Patient age, y/donor-recipient relationship
Age 18-54/parent donor	1.00, P < .0001§	1.00, P = .003§	1.00, P = .18§
Age 18-54/sibling donor	0.87 (0.61-1.24), P = .44	0.96 (0.51-1.82), P = .90	0.75 (0.52-1.09), P = .14
Age 18-54/offspring donor	0.92 (0.61-1.38), P = .67	1.47 (0.75-2.88), P = .26	0.65 (0.41-1.03), P = .07
Age 55-78/sibling donor	1.53 (1.04-2.23), P = .030	2.36 (1.26-4.45), P = .007	0.84 (0.54-1.30), P = .43
Age 55-78/offspring donor	1.57 (1.13-2.20), P = .008	1.84 (1.04-3.25), P = .04	0.96 (0.66-1.39), P = .82
Patient age/donor age, y
Age 18-54/donor age 10-29	1.00, P < .0001§	1.00, P = .001§	1.00, P = .28§
Age 18-54/donor age 30-80	1.07 (0.79-1.44), P = .64	1.12 (0.67-1.86), P = .42	1.13 (0.82-1.57), P = .44
Age 55-78/donor age 10-29	1.57 (1.09-2.26), P = .015	1.34 (0.76-2.56), P = .37	1.49 (0.99--2.24), P = .06
Age 55-78/donor age 30-80	1.82 (1.38-2.39), P < .0001	2.09 (1.32-3.34), P = .002	1.24 (0.89-1.71), P = .19

^*Adjusted for recipient CMV seropositivity, disease risk index, and disease.

^†Adjusted for recipient CMV seropositivity and graft type.

‡Adjusted for disease risk index, disease and graft type.

^§This P value represents the level of significance for the overall Cox regression model. P values for paired comparisons within the model were considered significant only when the P value for the overall model was significant.