Table 1.
Main characteristics of rat ESBL-producing K. pneumoniae and E. coli.
| Sample number | Bacterial species | Sampling point (UTM, city district) | Rat species | ST | Phenotypic resistance | Beta-lactam resistance genes | |
|---|---|---|---|---|---|---|---|
| MAIN CHARACTERISTICS | |||||||
| IMT38444 | K. pneumoniae | S 123 (28P 648851 1063078, Ratoma Kaporo) | R. rattus | ST-896 | CEF, TET, GEN, SXT, TOB | blaCTX−M−14, blaSHV−11−like, blaTEM−1B | |
| IMT38405 | K. pneumoniae | S 40 (28P 646660 1055837, Dixinn Gare Rail) | R. rattus | ST-307 | CEF, TET, ENR, GEN, TOB, SXT | blaCTX−M−15, blaOXA−1, blaSHV−28, blaTEM−1B | |
| IMT38403 | K. pneumoniae | S 75 (28P 657469 1066350, Matoto Enta Nord) | R. rattus | ST-502 | CEF, CAP, TET, SXT | blaCTX−M−9, blaDHA−1, blaSHV−62 | |
| IMT38402 | E. coli | S 75 (28P 657469 1066350, Matoto Enta Nord) | R. norvegicus | ST-38 | CEF, TET, SXT | blaCTX−M−15, blaTEM−1B | |
| IMT38406 | E. coli | S Abou (n.a., Ratoma Lambanyi) | R. rattus | ST-4684 | CEF, TET, SXT | blaCTX−M−15 | |
| IMT38404 | E. coli | S Abou (n.a., Ratoma Lambanyi) | R. rattus | ST-4684 | CEF, TET, SXT | blaCTX−M−15 | |
| Sample number | Aminoglycosides | Fluoroquinolones | Tetracyclines | Chloramphenicol | Sulfametoxazole/ Trimethoprim | Plasmid content | pMLST summary |
| ADDITIONAL GENOTYPIC RESISTANCE AND PLASMIDS | |||||||
| IMT38444 | aac(3)-IId-like, strA, strB | oqxA-like, oqxB-like, QnrS1 | tet(A), tet(D) | sul1, sul2, dfrA1 | IncFII, IncFIB(K), ColRNAI | IncF[K9:A-:B-] | |
| IMT38405 | aac(3)-IIa-like, strA-like, strB, aac(6')Ib-cr | oqxA-like, oqxB-like, QnrB66-like | tet(A) | catB3-like | sul2, dfrA14-like | IncFIB(K), IncFII(K) | IncF[K7:A-:B-] |
| IMT38403 | aadA5, strA-like | QnrB4 | tet(B)-like | catA1-like | sul1, dfrA1, dfrA15 | IncFIA(HI1), IncFIB(K), IncHI1B, IncR, ColRNAI | IncF[F-:A13*:B-] |
| IMT38402 | strA, strB | QnrS1 | tet(A) | catB1-like | sul2, dfrA14-like | IncFIB(K), IncFIB(AP001918), ColRNAI | IncF[F-:A-:B53] |
| IMT38406 | strA-like, strB | QnrS1 | tet(A)-like | sul2, dfrA14-like | ColRNAI | ||
| IMT38404 | strA-like, strB-like | QnrS1 | tet(A)-like | sul2, dfrA14-like | ColRNAI | ||
IMT, Institut für Mikrobiologie und Tierseuchen; ST, sequence type; CEF, cefotaxime; CHL, chloramphenicol; ENR, enrofloxacin; GEN, gentamicin; SXT, sulfamethoxazole; TET, tetracycline; TOB, tobramycin. ColRNAI is a small colicin plasmid, n.a. non available.