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. 2018 Feb 9;9:110. doi: 10.3389/fpls.2018.00110

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Copyright © 2018 Hu, Ren, Peng, Umana, Le, Danilova, Fu, Wang, Robertson, Hulbert, White and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Candidate disease-associated genes identified via XP-CNV. (A) A genome-wide view of the distribution of sequencing depth comparison between highly R pools and highly S pools across 10 maize chromosomes. Each dot designates a gene. Y-axis represents log2 values of ratios of read depths of R to S, signifying CNV between R and S pools. Genes with statistically significantly higher and lower read depths of R vs. S pools were interpreted as Up-CNV (green) and Dn-CNV (blue), respectively. Orange boxes indicate centromeric positions. Red arrow points to the rp1 locus. (B) Read depths (reads per gigabit total aligned reads, RPG) across the Up-CNV gene GRMZM2G083246 from the pools of two highly R (R2 and R3) and two highly S (S1 and S3) pools.