Table 1.
Comparison of a broad selection of cell surface molecules expressed by mast cells and eosinophils.
| Mast Cells | Eosinophils | ||
|---|---|---|---|
| Fc Receptors | FcγRI (CD64) | + 30,31 | — |
| FcγRII (CD32) | + 32,33 | + 34–37 | |
| FcγRIIa | + 32,39 | + 39 | |
| FcγRIIb | + 40,41 | — | |
| FcγRIII (CD16) | — | + 42–44 | |
| FcεRI | + 45–49,51–53,280 | — | |
| FcεRII (CD23) | — | + 57 | |
| FcαRI | — | + 59,60 | |
| Siglecs | Siglec-2 | + 61 | — |
| Siglec-3 | + 61 | + 281 | |
| Siglec-5 | + 61 | — | |
| Siglec-6 | + 61 | — | |
| Siglec-7 | + 62 | + 281 | |
| Siglec-8 | + 61,64,67 | + 64–66,68 | |
| Siglec-10 | + 61 | + 69 | |
| CD300 Receptors | CD300a | + 70,71 | + 72 |
| CD300c | + 73 | — | |
| CD300f | + 75,77 | + 75,76 | |
| Leukocyte Ig-like Receptors (LILR) | LILRA1 | + 80 | — |
| LILRA2 | — | + 79 | |
| LILRB1 | + 80 | + 79 | |
| LILRB2 | + 80 | + 79 | |
| LILRB3 | + 80 | + 79 | |
| LILRB4 | + 80 | — | |
| LILRB5 | + 80 | — | |
| Cytokine Receptors | IL-4R | + 82–84 | + 20,81 |
| IL-5R | ± 90 | + 19,86 | |
| IL-13Rα1 | + 45,95 | + 94 | |
| c-kit (CD117) | + 96,101,102 | + 100 | |
| TSLPR | + 106,107 | + 109,110 | |
| IL1RL1 (ST2) | + 115–119 | + 18,68,122–125 | |
| Migratory Receptors and Others | α4β1 integrin (VLA-4) | + 129,131 | + 128,132,133 |
| α4β7 integrin | + 131,134,135,139 | + 66,136–138 | |
| CRTH2 | ± 144 | + 140–142 | |
| C3aR | + 152,153 | + 149,150 | |
| C5aR | + 152 | + 150,151 | |
| C5aR2 | + 156 | ± 157 | |
| S1PR1 | + 159 | + 162 | |
| S1PR2 | + 154,155,159–161 | — | |
| S1PR3 | — | + 162 | |
| S1PR4 | — | + 162 | |
| S1PR5 | — | + 162 | |
| H1R | + 171 | + 164 | |
| H2R | + 171 | + 165 | |
| H4R | + 163,168 | + 166,167 | |
| CB1 | + 282–284 | — | |
| CB2 | + 283 | + 172,173 | |
| TLRs | ± 176,177 | ± 176,177 | |
| CD48 | + 180 | + 181,182,184 | |
| 2B4 (CD244) | ± 98 | + 72,179,183 |
Abbreviations: Immunoglobulin (Ig) G receptor (FcγR), IgE receptor (FcεR), IgA receptor (FcαR), (Sialic acid-binding Ig-type lectin (Siglec), Leukocyte Ig-like receptor (LILR), Interleukin 1 receptor-like 1 (IL1RL1), Prostaglandin D2 receptor 2 (CRTH2), Sphingosine-1-phosphate receptor (S1PR), Histamine receptor (HR), Cannabinoid receptor (CB), Toll-like receptor (TLR), Natural killer cell receptor (2B4).