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Albuminuria and serum cystatin C levels in young (Y), middle-aged (M), and old (O) mice. (A) Urinary albumin to creatinine ratio in young (Y), middle-aged (M), and old (O) mice. Data from 5 to 9 mice in each group are shown (**P < 0.01 vs. young mice by ANOVA). (B) Serum cystatin C level bears an inverse relation to glomerular filtration function. Data from 5 to 6 mice in each group are shown (*P < 0.05 vs. young by ANOVA).
