Table 1. Age and vaccination coverage for children < 60 months admitted for rotavirus during rotavirus seasons (Jan-Jun) before and after vaccine introduction1.
Pre-Vaccine (2002–2005) | Early Post-Vaccine (2008–2011) | Late Post-Vaccine (2012–2015) | |||||||
---|---|---|---|---|---|---|---|---|---|
Odd Seasons | Even Seasons | p-value | Odd Seasons | Even Seasons | p-value | Odd Seasons | Even Seasons | p-value | |
Hospitalizations, n | 667 | 458 | 426 | 185 | 165 | 45 | |||
Hospitalization rate2 (per 10,000 p-y) | 47.8 | 44.4 | 0.24 | 10.6 | 5.6 | <.0001 | 4.0 | 0.96 | <.0001 |
95% CI | 44.3–51.5 | 40.6–48.7 | 9.7–11.7 | 4.9–6.5 | 3.5–4.7 | 0.72–1.29 | |||
Median age (mo) | 14 | 12 | <.0001 | 18 | 14 | 0.0002 | 17.5 | 15 | 0.27 |
IQR | 10–20 | 9–18 | 11–28 | 8–22 | 9–29 | 7–27 | |||
Rotavirus vaccine-eligible hospitalizations, n | N/A | 401 | 147 | 172 | 45 | ||||
Vaccine coverage | 19% | 15% | 0.25 | 41% | 49% | 0.32 | |||
95% CI | 15–23% | 9–21% | 33–48% | 34–64% |
1. 2006–2007 excluded as transition years
2. Hospitalization rate for children 0–59 months
Abbreviation: P-y = person-years