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. 2018 Feb 14;13(2):e0191429. doi: 10.1371/journal.pone.0191429

Table 1. Age and vaccination coverage for children < 60 months admitted for rotavirus during rotavirus seasons (Jan-Jun) before and after vaccine introduction1.

Pre-Vaccine (2002–2005) Early Post-Vaccine (2008–2011) Late Post-Vaccine (2012–2015)
Odd Seasons Even Seasons p-value Odd Seasons Even Seasons p-value Odd Seasons Even Seasons p-value
Hospitalizations, n 667 458 426 185 165 45
Hospitalization rate2 (per 10,000 p-y) 47.8 44.4 0.24 10.6 5.6 <.0001 4.0 0.96 <.0001
95% CI 44.3–51.5 40.6–48.7 9.7–11.7 4.9–6.5 3.5–4.7 0.72–1.29
Median age (mo) 14 12 <.0001 18 14 0.0002 17.5 15 0.27
IQR 10–20 9–18 11–28 8–22 9–29 7–27
Rotavirus vaccine-eligible hospitalizations, n N/A 401 147 172 45
Vaccine coverage 19% 15% 0.25 41% 49% 0.32
95% CI 15–23% 9–21% 33–48% 34–64%

1. 2006–2007 excluded as transition years

2. Hospitalization rate for children 0–59 months

Abbreviation: P-y = person-years