Table 2. Age and vaccination coverage for children < 60 months admitted for acute gastroenteritis during rotavirus seasons (Jan-Jun) before and after vaccine introduction1.
Pre-Vaccine (2002–2005) | Early Post-Vaccine (2008–2011) | Late Post-Vaccine (2012–2015) | |||||||
---|---|---|---|---|---|---|---|---|---|
Odd Seasons | Even Seasons | p-value | Odd Seasons | Even Seasons | p-value | Odd Seasons | Even Seasons | p-value | |
Hospitalizations, n | 1,823 | 1,271 | 2,424 | 1,786 | 1,547 | 1,620 | |||
Hospitalization rate2 (per 10,000 p-y) | 131.2 | 124.0 | 60.7 | 54.4 | 38.0 | 34.8 | |||
95% CI | 125.3–137.3 | 117.4–131.0 | 58.4–63.2 | 51.9–57.0 | 36.1–39.9 | 33.1–36.5 | |||
Median age (mo) | 13 | 11 | <.0001 | 11 | 10 | <.0001 | 12 | 10 | <.0001 |
IQR | 7–20 | 6–17 | 4–22 | 3–17 | 5–23 | 3–20 | |||
Rotavirus vaccine-eligible hospitalizations, n | N/A | 2,187 | 1,474 | 1,515 | 1,524 | ||||
Vaccine coverage | 51% | 52% | 0.43 | 68% | 71% | 0.06 | |||
95% CI | 49–53% | 50–55% | 66–71% | 69–74% |
1. 2006–2007 excluded as transition years
2. Hospitalization rate for children 0–59 months
Abbreviation: P-y = person-years