Table 1. The role of miRs in several bone cell types.
Bone Cell Type | Cell Role | miR Involved |
---|---|---|
MSCs | Proliferation and homeostasis | miR-135, miR-138, miR-23a, miR-30c, miR-31, miR-196a, miR-204, miR-206, miR-335 |
Pre-osteoblast | Proliferation | miR-23, miR-29, miR-34, miR-30, miR-31 miR-210 miR-218 |
Osteoblast | Matrix Maturation | miR-125b, miR-138, miR-637, miR-29c |
Osteocytes | Mineralization | miR-23a~27a~24–2, miR-204, miR-205, miR-217, miR-133, miR-135 |
Role of miRs in mesenchmal stem cells and multiple bone cell types. Adapted from Lain and Stein et al, and Baglìo and DeVescovi et al.