Table 3.
Multivariable Regression Results: Cox Proportional Hazard (All-Cause) and Competing Risk (Death From Lung Cancer and Death From Competing Causes)
| Covariate | Death from All Causesa |
Death from Lung Cancerb |
Death from Competing Causesb |
|||
|---|---|---|---|---|---|---|
| Adjusted OR | 95% CI | Adjusted RR | 95% CI | Adjusted RR | 95% CI | |
| Race/ethnicity (reference: Non-Hispanic white) | ||||||
| Hispanic | 0.93 | 0.89-0.98 | 0.95 | 0.90-1.01 | 0.87 | 0.80-0.94 |
| Non-Hispanic Asian | 0.82 | 0.79-0.86 | 0.87 | 0.83-0.92 | 0.77 | 0.71-0.83 |
| Non-Hispanic black | 1.05 | 1.02-1.08 | 1.00 | 0.96-1.04 | 1.07 | 1.02-1.12 |
| Female sex (reference: Male sex) | 0.79 | 0.77-0.80 | 0.89 | 0.87-0.91 | 0.77 | 0.75-0.8 |
| Age at diagnosis, y (reference: 40-44 y) | ||||||
| 45-49 | 1.22 | 1.05-1.42 | 1.14 | 0.96-1.35 | 1.17 | 0.88-1.57 |
| 50-54 | 1.36 | 1.18-1.56 | 1.22 | 1.04-1.43 | 1.23 | 0.94-1.61 |
| 55-59 | 1.51 | 1.32-1.74 | 1.33 | 1.14-1.55 | 1.40 | 1.08-1.82 |
| 60-64 | 1.70 | 1.48-1.95 | 1.44 | 1.23-1.67 | 1.55 | 1.19-2.01 |
| 65-69 | 1.87 | 1.64-2.14 | 1.49 | 1.28-1.73 | 1.76 | 1.36-2.28 |
| 70-74 | 2.17 | 1.89-2.48 | 1.57 | 1.35-1.83 | 2.11 | 1.63-2.73 |
| 75-79 | 2.56 | 2.24-2.93 | 1.73 | 1.48-2.01 | 2.49 | 1.93-3.22 |
| 80-84 | 2.80 | 2.44-3.20 | 1.83 | 1.58-2.14 | 2.60 | 2.01-3.37 |
| ≥ 85 | 3.26 | 2.85-3.74 | 1.85 | 1.58-2.16 | 2.90 | 2.24-3.76 |
| Histologic type (reference: adenocarcinoma) | ||||||
| Other non-small cell | 1.25 | 1.22-1.28 | 1.10 | 1.07-1.13 | 1.33 | 1.29-1.38 |
| Small cell | 1.30 | 1.24-1.35 | 1.39 | 1.32-1.46 | 0.96 | 0.88-1.04 |
| Squamous cell | 1.22 | 1.20-1.25 | 1.12 | 1.09-1.15 | 1.27 | 1.22-1.31 |
| Stage at diagnosis (reference: IA) | ||||||
| IB | 1.47 | 1.44-1.50 | 1.72 | 1.68-1.77 | 0.88 | 0.85-0.91 |
| IIA | 1.59 | 1.53-1.66 | 1.93 | 1.83-2.02 | 0.91 | 0.84-0.97 |
| IIB | 2.00 | 1.95-2.05 | 2.59 | 2.51-2.67 | 0.74 | 0.7-0.77 |
| Type of surgical resection (reference: none) | ||||||
| < 1 lobe | 0.46 | 0.45-0.48 | 0.50 | 0.48-0.52 | 0.92 | 0.88-0.96 |
| ≥ 1 lobe | 0.33 | 0.32-0.34 | 0.38 | 0.37-0.39 | 0.78 | 0.76-0.81 |
| Radiation sequence (reference: none) | ||||||
| Before surgery | 1.07 | 1.03-1.11 | 1.22 | 1.17-1.28 | 0.88 | 0.81-0.94 |
| Before and after surgery | 1.24 | 0.97-1.58 | 1.40 | 1.07-1.83 | 0.92 | 0.55-1.54 |
| After surgery | 1.15 | 1.05-1.26 | 1.20 | 1.08-1.34 | 1.12 | 0.94-1.33 |
| Given but sequence unknown | 1.35 | 0.98-1.84 | 1.66 | 1.17-2.36 | 0.79 | 0.4-1.54 |
RR = relative risk.
a
Cox proportional hazard (all-cause) model.
b
Competing risk (death from lung cancer and death from competing causes) model.