Table 2.
Predictive Performance of PEF Alone, CAPTURE Alone, and CAPTURE Plus Selective Use of PEF
| Score Cutoff (Performance Indicator) | Case Subjectsa Vs Control Subjectsb (N = 30) |
Case Subjectsa Vs No COPDc (n = 27) |
|---|---|---|
| PEF alone; threshold (male subjects < 350; female subjects < 250) | ||
| Sensitivity | 88.2% | 88.2% |
| Specificity | 84.6% | 100% |
| Overall error | 13.3% | 7.4% |
| CAPTURE alone; scores ≥ 2 | ||
| Sensitivity | 100% | 100% |
| Specificity | 61.5% | 70.0% |
| Overall error | 16.7% | 11.1% |
| CAPTURE + PEF 0–1 = control; score 5–6 = case Score 2, 3, 4 = PEF used for group assignment |
||
| Sensitivity | 88.2% | 88.2% |
| Specificity | 92.3% | 100% |
| Overall error | 10.0% | 7.4% |
CAPTURE = COPD Assessment in Primary Care to Identify Undiagnosed Respiratory Disease and Exacerbation Risk; PEF = peak expiratory flow.
a
Clinically significant COPD (FEV1 < 60% predicted or exacerbation risk).
b
COPD with FEV1 > 60% and exacerbation free > 12 months; or no known diagnosis or treatment for COPD and an EV1/FVC ratio > 0.70.
c
No known diagnosis or treatment for COPD and an FEV1/FVC ratio > 0.70.