Skip to main content
. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Hypertension. 2018 Jan 29;71(3):429–436. doi: 10.1161/HYPERTENSIONAHA.117.10289

Table 5.

Coefficients for Multivariable Linear Regression of the associations between cognitive test scores and left ventricular functional parameters

Digit Span
CASI DSC Forward Backward
Systolic function
  LV ejection fraction, (%) −0.099 (−2.345–1.751) 0.79 0.009 (−1.281–0.127) 0.24 0.039 (−0.172–0.251) 0.49 0.012 (−0.151–0.014) 0.81
  Stroke volume, (ml) −0.064 (−0.121–0.672) 0.89 0.010 (−0.721–1.281) 0.33 0.044 (−0.172–0.239) 0.46 −0.014 (−0.412–0.011) 0.82
  LV circumferential strain, (%) −0.027 (−1.231–1.145) 0.92 −0.015 (−0.192–0.123) 0.12 0.08 (−0.152–0.381) 0.61 0.023 (−0.126–0.131) 0.56
Diastolic function
  LV torsion recoil, (deg/cm/ms) −1.839 (−4.261–1.189) 0.23 −0.006 (−0.716–0.912) 0.82 −0.09 (−0.712–0.012) 0.54 −0.130 (−0.812–0.182) 0.44
  Log (Strain Relaxation Index), (ms/%) 0.046 (−.1.124–0.812) 0.71 0.046 (−0.012–0.329) 0.48 −0.007 (−0.192–0.015) 0.34 −0.008 (−0.182–0.081) 0.35
  Log (Early Diastolic Strain Rate), (%/ms) −0.010 (−1.241–0.871) 0.22 0.001 (−0.012–0.001) 0.21 −0.001 (−0.193− 0.028) 0.34 0.009 (−0.124–0.301) 0.19
LV structural indices
  LV mass index, (g/m2) −2.367 (−4.110– −1.231) 0.002 −0.105 (−0.691– −0.012) 0.001 −0.23 (−1.231– −0.001) 0.01 −0.449 (−1.192– −0.012) 0.001
  LV mass-to-volume ratio, (g/ml) −0.030 (−0.078– −0.001) 0.013 −0.001 (−0612– −0.000) 0.001 −0.003 (−0.191– −0.000) 0.009 −0.005 (−0.017– −0.000) 0.001

Coefficients and 95% confidence intervals (in brackets) for multivariable linear regression model to assess the associations between CMR variables with different cognitive performance domains. Models adjusted for demographics including age, gender, race/ethnicity, level of education and income level, risk factors including systolic blood pressure, diastolic blood pressure, pulse pressure, use of antihypertensives, resting heart rate, high-density lipoprotein, low-density lipoprotein, fasting glucose level, body mass index, diabetes, CRP levels, cigarette smoking, alcohol use, coronary artery calcium score and cardiovascular events including coronary events (myocardial infarction and resuscitated cardiac arrest), heart failure, coronary revascularization (percutaneous coronary intervention or coronary artery bypass surgery) and clinical stroke during the follow-up period.

CASI: Cognitive Abilities Screening Instrument, DSC: Digit Symbol Coding