Table 2.

Comparison of post-operative serum cortisol in patients achieving early remission by POD-10. Results of AUROC analyses with recurrence as the reference variable. Remission defined as cortisol nadir ≤5µg/dL. Recurrence defined by biochemical hormone levels, clinical stigmata or medication requirement.

Cortisol	AUROC	95% CI	Std dev	n	P value
0000hr POD-1	0.775	0.64, 0.91	0.067	94	0.010**
0600hr POD-1	0.839	0.74, 0.94	0.052	119	<0.001***
1200hr POD-1	0.761	063, 0.89	0.068	103	0.015*
1800hr POD-1	0.724	0.52, 0.93	0.105	98	0.039*
0600hr POD-3	0.742	0.63, 0.85	0.056	228	<0.001***
1200hr POD-3	0.753	0.53, 0.97	0.111	52	0.044*
1800hr POD-3	0.897	0.77, 1.03	0.055	42	0.023*
NEPV cortisol	0.832	0.72, 0.94	0.055	65	0.007**
Nadir ≤5µg/dL	0.714	0.60, 0.83	0.058	241	0.001***
Nadir ≤2µg/dL	0.661	0.51, 0.80	0.073	222	0.050*

(Abbreviations: POD, post-operative day; NEPV, normalised early post-operative value, AUROC, area under the receiver operating curve; CI, confidence interval; Std dev, standard deviation; n, number; p value, probability value).