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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Br J Dermatol. 2018 Jan 3;178(2):350–356. doi: 10.1111/bjd.15896

Figure 4.

Figure 4

Summary of colchicine’s actions in clinical applications. Colchicine interacts with tubulin, altering the tubulin – microtubule balance. This change in the dynamics of the cellular microtubule arrays results leads to changes in cell motility / chemotaxis, as well as changes in secretion, as indicated in the figure.