Figure 2.
Distribution of Unpruned 1000 Genomes Imputed SNPs Assessed for Association with Methylation Relative to the CpG Location (±25 kb)
SNP position relative to the replicated methylation CpG position (X = 0) is plotted against –log10 of the p value for meQTL meta-analysis in each race. SNPs above the red line are significant after Bonferroni correction for multiple testing (p < 3.0 × 10−5). Abbreviations: AA, African American; bp, base pair; CpG, cytosine-phosphate-guanine; EA, European ancestry; meQTL, methylation quantitative trait locus; SNP, single-nucleotide polymorphism.