Table 1.
Group characteristics of hypertrophic cardiomyopathy cohort
| All (n = 288) | Patients with previous aborted sudden cardiac death or equivalent events (n = 14) | Patients without previous aborted sudden cardiac death or equivalent events (n = 274) | p-value* | |
|---|---|---|---|---|
| Male | 191 (66%) | 10 (71%) | 181 (66%) | 0.68 |
| Age (years) | 52 ± 16 | 41 ± 18 | 53 ± 15 | <0.01 |
| Syncope | 34 (12%) | 5 (36%) | 29 (11%) | <0.01 |
| Family history of sudden cardiac death | 40 (14%) | 9 (64%) | 31 (11%) | <0.001 |
| Maximal left ventricular wall thickness ≥30 mm | 16 (6%) | 0 | 16 (6%) | 0.35 |
| Left ventricular hypertrophy thickness (mm) | 20 ± 5 | 22 ± 4 | 20 ± 5 | 0.14 |
| Non-sustained ventricular tachycardia | 66 (23%) | 9 (64%) | 5 (2%) | <0.001 |
| Abnormal blood pressure response to exercise | 32/184 (17%) | 1/7 (14%) | 31/177 (18%) | 0.83 |
| Maximal left ventricular outflow tract gradient (mmHg) | 28 ± 41 | 17 ± 26 | 28 ± 42 | 0.33 |
| Left atrial diameter (mm) | 41 ± 7 | 41 ± 8 | 41 ± 7 | 1.00 |
| Late gadolinium enhancement on cardiac magnetic resonance imaging | 127/195 (65%) | 4/5 (80%) | 123/190 (65%) | 0.48 |
| Atrial fibrillation | 57 (20%) | 6 (43%) | 47 (17%) | 0.02 |
| 0 risk factors | 158 (55%) | 1 (7%) | 157 (57%) | <0.001 |
| 1 risk factors | 81 (28%) | 5 (36%) | 76 (28%) | 0.52 |
| ≥2 risk factors | 49 (17%) | 8 (57%) | 41 (15%) | <0.0001 |
Values are presented in absolute numbers (percentages) and mean ± standard deviation.
*
Comparison between patients with and without previous aborted sudden cardiac death or equivalent events.