Table 2.
Association of biomarkers of Intestinal inflammation, proliferation and regeneration with growth faltering during the first 18 months of life (n = 272).
| Biomarker | 6 month | 9 month | |||||
|---|---|---|---|---|---|---|---|
| *Quartiles cutoff | **Change in HAZ per year compared to q1 | (P-trend) p value | Quartiles cutoff | Change in HAZ per year compared to q1 | (P-trend) p value | ||
| GLP2 (serum) (ng/ml) | q1 | 2539 | Ref | (0.035) | 3789 | Ref | (0.045) |
| q2 | 7383 | 0.019 | 0.880 | 8513 | 0.101 | 0.436 | |
| q3 | 11817 | −0.212 | 0.099 | 12346 | −0.000 | 0.998 | |
| q4 | 429763 | −0.271 | 0.039 | 75442 | −0.267 | 0.038 | |
| Fecal Reg-1b (pg/ml) | q1 | 73 | Ref | (0.694) | 79 | Ref | (0.646) |
| q2 | 153 | −0.084 | 0.507 | 178 | 0.199 | 0.118 | |
| q3 | 272 | 0.031 | 0.806 | 328 | 0.013 | 0.914 | |
| q4 | 1237 | −0.051 | 0.688 | 1377 | −0.071 | 0.576 | |
| Fecal NEO (nmol/L) | q1 | 275 | Ref | (0.078) | 400 | Ref | (0.054) |
| q2 | 475 | −0.031 | 0.802 | 574 | 0.231 | 0.063 | |
| q3 | 725 | −0.137 | 0.268 | 725 | 0.239 | 0.065 | |
| q4 | 4400 | −0.216 | 0.092 | 4400 | 0.013 | 0.915 | |
| Fecal MPO (ng/ml) | q1 | 6050 | Ref | (0.005) | 1500 | Ref | (0.302) |
| q2 | 14300 | −0.008 | 0.948 | 5550 | −0.367 | 0.003 | |
| q3 | 35200 | −0.126 | 0.317 | 16100 | −0.397 | 0.001 | |
| q4 | 95600 | −0.207 | 0.099 | 80200 | −0.257 | 0.042 | |