Table 2.

The full Cox regression model for the endpoint of any thrombo‐occlusive event or death in the full study population and the ischemic stroke subpopulation

	HR	95% CI	P value
Full population
CYP2C19, additive	1.29	1.04–1.59	0.019
Age, years	1.01	1.00–1.02	0.206
Male sex	0.93	0.74–1.18	0.561
Aspirin use	0.92	0.73–1.16	0.483
PPI use	1.02	0.77–1.36	0.887
Ischemic stroke subpopulation
CYP2C19, additive	2.23	1.17–4.24	0.015
Age, years	1.01	0.97–1.05	0.653
Male sex	0.66	0.30–1.43	0.287
Aspirin use	0.25	0.03–1.95	0.186
PPI use	2.12	0.83–5.38	0.114

CI, confidence interval; HR, hazard ratio; PPI, proton pump inhibitor.