Table 1.
Demographics and clinical scores
| Controls (N = 23) | LBD (N = 32) | Between‐group differences (P value) | |
|---|---|---|---|
| Age | 76.3 (5.5) | 75.0 (6.4) | T 53 = 0.76; P = 0.45 |
| Sex male:female | 16:7 | 27:5 | χ 2 = 1.7; P = 0.2 |
| Education years | 11.7 (2.3) | 10.5 (2.5) | T 53 = 1.9; P = 0.06 |
| Duration (years) cognitive decline | ‐ | 3.33 (2.07) | |
| Cholinesterase Inhibitors | 0 (0%) | 27 (84%) | ‐ |
| Ldopa equivalent dose | ‐ | 683.9 (450.1) [N = 21] | |
| Positive DAT scan | ‐ | 10/11 (91%) | |
| UPDRS | 1.3 (1.7) | 19.06 (8.0) | |
| MMSE | 29.1 (0.9) | 23.4 (3.8) | |
| CAMCOG | 96.8 (3.6) | 76.7 (12.6) | |
| Mean xyz motion (mm) | 0.139 (0.04) | 0.145 (0.08) | T 53 = 0.33; P = 0.74 |
| Max xyz motion (mm) | 0.602 (0.27) | 0.618 (0.31) | T 53 = 0.21; P = 0.84 |
| Mean angular motion (°) | 0.062 (0.012) | 0.088 (0.060) | T 53 = 2.07; P = 0.043 |
| Max angular motion (°) | 0.463 (0.28) | 0.491 (0.28) | T 53 = 0.36; P = 0.72 |
| Mean DVARS | 1.36 (0.14) | 1.36 (0.19) | T 53 = 0.01; P = 1.0 |
| Max DVARS | 4.32 (1.76) | 3.85 (1.18) | T 53 = 1.18; P = 0.24 |
CAMCOG, Cambridge Cognitive Examination; MMSE, Mini‐Mental State Examination; UPDRS, Unified Parkinson's disease rating scale.
DVARS per‐image standard deviation of the temporal derivative.