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. 2017 Nov 22;19(1):48–52. doi: 10.1002/cbic.201700586

Table 1.

The parallel artificial membrane permeability assay (PAMPA).[a]

Compound Permeability −log P e Compound Permeability −log P e
[nm s−1] [nm s−1]
II 7.6 5.12 II′ 12 4.96
III <0.01 III′ 10 4.99
IV 6.0 5.22 IV′ 13 4.90

[a] Permeability was measured at pH 7.4 and at room temperature, the value is reported as an average of quadruplicates.