Table 1.
Compound | Permeability | −log P e | Compound | Permeability | −log P e |
---|---|---|---|---|---|
[nm s−1] | [nm s−1] | ||||
II | 7.6 | 5.12 | II′ | 12 | 4.96 |
III | <0.01 | III′ | 10 | 4.99 | |
IV | 6.0 | 5.22 | IV′ | 13 | 4.90 |
[a] Permeability was measured at pH 7.4 and at room temperature, the value is reported as an average of quadruplicates.