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. 2017 Oct 16;8(1):1–10. doi: 10.1111/cob.12226

Figure 3.

Figure 3

Proportion of subjects with meaningful estimated mean change from baseline to 3 years in HRQoL for IWQOL‐Lite total score and SF‐36 summary scores. Meaningful estimated mean change from baseline to Week 160 (LOCF) was defined differently for the IWQOL‐Lite and the SF‐36 according to published algorithms. The data was analysed in an ordinal regression using a cumulative logit link. The model includes treatment, sex, country, BMI stratification factor as fixed factors and the baseline HRQoL score (IWQOL‐Lite total score, SF‐36 PCS score or SF‐36 MCS score, as appropriate) as a covariate. Graphs are estimated proportions. OR for response classes was calculated as the ratio of results from participants receiving liraglutide 3.0 mg and placebo. BMI, body mass index, CI, confidence interval; HRQoL, health‐related quality of life; IWQOL‐Lite, Impact of Weight on Quality of Life‐Lite, LOCF, last observation carried forward; MCS, mental component summary; OR, odds ratio; PCS, physical component summary; SF‐36, Short‐Form 36 v2.