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. 2017 Sep 15;18(2):444–452. doi: 10.1111/ajt.14458

Table 1.

Grading of infection and rejection

A. Radiology B. Bronchoscopy C. Clinical criteria D. Microbiology E. Transbronchial biopsies (TBB)
New or increasing radiographic changes on chest X‐ray or CT scan One or more of the following endobronchial abnormalities:

  • Inflamed endobronchial mucosa

  • Endobronchial lesion (white/yellow) with/without necrotic changes

  • Purulent secretion

  • Inflammatory cells in cytology and/or PAD

 One or more of the following conditions:

  • New or increased cough, dyspnea, increased sputa.

  • Fever >38°C

  • Worsening gas exchange

  • White blood cell count >15

 One or more of the following:

  • Bacterial growth in BALF

  • Fungal growth in BALF

  • Positive viral PCR in BALF

  • Positive CMV PCR in blood

 Positive histopathology for rejection

Definite infection

3

 A, B, C and D No

Probable infection

2

 A and/or B C or D No

Possible infection

1

 No B or D None B or D No
No infection 0 No None None No No
Rejection R – – – – Yes