Table 1.
Description and distribution of variables and models for dietary exposure assessment of OP residues in tea infusion
| Compound | Variables | Definition | Assumption/distribution/formula | Source |
|---|---|---|---|---|
| OPs | Conc Qp | Concentration in methamidophos equivalents of OPs in tea infusion (detected value) | Lognorm (0.052, 4.636)a | Monitoring data |
| Lognorm (0.003, 0.041)b | ||||
| Lognorm (0.003, 0.151)c | ||||
| Conc Qn | Concentration in methamidophos equivalents of OPs in tea infusion (undetected value) | Uniform (0, 0.105)a | Monitoring data | |
| Uniform (0, 0.044)b | ||||
| Uniform (0, 0.105)c | ||||
| Conc * Qp | Concentrationin in methamidophos equivalents of OPs in tea infusion (detected value) | Lognorm (0.038, 2.987)a | Monitoring data | |
| Lognorm (0.002, 0.019)b | ||||
| Lognorm (0.001, 0.019)c | ||||
| Conc * Qn | Concentration in methamidophos equivalents of OPs in tea infusion (undetected value) | Uniform (0, 0.447)a | Monitoring data | |
| Uniform (0, 0.235)b | ||||
| Uniform (0, 0.447)c | ||||
| Pp | Rate of sample with detectable | 10.11%a | Calculated | |
| 13.53%b | ||||
| 6.20%c | ||||
| Pn | Rate of sample with undetectable | 89.89%a | Calculated | |
| 86.47%b | ||||
| 93.80%c | ||||
| Conc QC | Concentration in methamidophos equivalents of OPs in tea infusion | Discrete (ConcQp: ConcQn, Pp: Pn) | Calculated | |
| TR | Transfer rate | 87.4% | Based on the open scientific literatures to calculate | |
| 22.1% | ||||
| 2.8% | ||||
| Cons | The consumption of tea | Invgauss (3.772, 0.721)a | China National Nutrient and Health Survey | |
| Invgauss (4.474, 1.718)b | ||||
| Invgauss (11.532, 10.870)c | ||||
| BW | Body weight for tea consumers | Normal (55.1, 15.5) | China National Nutrient and Health Survey |
For ConcQp and ConcQn mark with an asterisk (*), RPFs were calculated based on CED at 20% AChE inhibition in rat brain, IC for OPs is methamidophos
For ConcQp and ConcQn, RPFs were calculated based on BMDat 10% AChE inhibition in rat brain, IC for OPs is methamidophos
The 87.4, 22.1 and 2.8% were TRs of soluble OPs, moderately soluble OPs and low soluble OPs, respectively
aNon-fermented tea
bSemi-fermented tea
cFermented tea