Table 2.
Baseline characteristics
| Group | Gender | Age | Genotype (n) | Pancreatic Insufficient (%) | CFRD (%) | Bcc Species Isolated (n) | Additional Pathogens (n) | FEV1% Predicted | BMI |
|---|---|---|---|---|---|---|---|---|---|
| Eradication (n = 6) |
50% F | 23.3 (20–27) | dF508/dF508 [6] | (100%) | 83% | B. multivorans [4] B. gladioli [2] B. cepacia [1] |
PsA [6] MRSA [3] Steno [2] Aspergillus [2] |
65.5 (30–96%) | 20.2 (15.6–26.9) |
| Usual Care (n = 4) |
50% F | 28.2 (21–47) | dF508/dF508 [1] 405 3AtoC/V317A Q98X [1] dF508/Q98X [1] dF508/G542X [1] |
(75%) | 75% | B. multivorans [1] B. cepacia [2] B. arboris [1] |
PsA [3] MRSA [4] |
55.7 (31–98%) | 20.3 (18.9–22) |
Abbreviations: F=Female, CFRD- CF Related Diabetes, MRSA- Methicillin Resistant Staphylococcus aureus, PsA- Pseudomonas aeruginosa, Steno- Stenotrophomonas maltophilia