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. 2018 Feb 14;9:37. doi: 10.1186/s13287-018-0772-x

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Effects of LY294002 on the serum levels of E₂, FSH, LH, AMH, AZPAb and IL-17 in POF mice with or without hPMSC transplantation. a Estradiol (E₂) release. b Follicle stimulation hormone (FSH) release. c Luteinizing hormone (LH) release. d Anti-Müllerian hormone (AMH) release. e Anti-Zona pellucida antibody (AZPAb) release. f Interleukin (IL)-17 release. Data presented as mean ± SD. ^**P < 0.01, ^***P < 0.001 vs POF group. Groups: C control, M POF, T POF + hPMSCs, L POF + hPMSCs + LY294002, D POF + hPMSCs + DMSO. POF premature ovarian failure, hPMSC human placenta-derive mesenchymal stem cell, DMSO dimethylsulfoxide