Table 2: Clinical/outcomes inputs.

	Value	Source
Average number of severe hypoglycaemic events per year in T1D children	0.32	20–23
Average number of severe hypoglycaemic events per year in T1D adults	1	24–31
Increased risk for severe hypoglycaemia among patients with hypoglycaemia unawareness	6-fold	19, 32
Severe hypoglycaemic events requiring ambulance	86%	48
Severe hypoglycaemic events requiring accident and emergency	59%	48
Severe hypoglycaemic events requiring hospital admissions	20%	48
Reduction in severe hypoglycaemic events conferred by CGM	59%	33
Reduction in HbA1c conferred by CGM versus SMBG	0.6%	8
SMBG group: Frequency of fingersticks use	*8	49
CGM intervention group: Frequency of fingersticks use	2.8	38
Avoided pump usage every year	30%	36, 8

*NICE guideline NG18 recommends self-monitoring ≥5 times per day in children, and one study in the report had a 90th percentile frequency of SMBG of 37/week. The target population will have diabetes that is more difficult to manage than average, and many will wish to test more often because of a fear of hypoglycaemia. On this basis, the model assumes a testing frequency of eight per day. CGM = continuous glucose monitoring; HbA1c = glycated haemoglobin; SMBG = self-monitoring of blood glucose; T1D = type 1 diabetes.