Figure 6.

Model for PIF7 and MRGs in regulating the shade-induced hypocotyl elongation. Under shade, the transcription factor PIF7 is getting dephosphorylated and subsequently binds to the cis-element G-box of a target gene (e.g. YUCCA8, PRE1, or IAA19). Physical interactions between PIF7 and the H3K4me/H3K36me-reader MRG as well as between MRG and a histone-acetyltransferase HAT lead to formation of a multiprotein complex to acetylate nucleosomal histones to promote the target gene transcription within chromatin.