Table 2.
GABA+ and Glx ratios obtained from the primary analysis using GANNET for the SM voxel, along with associated data quality metrics
| Neurometabolite | Pre 1 | Pre 2 | Post Ex 1 (24 min) | Post Ex 2 (38 min) | Post Ex 3 (46 min) | rmANOVA | Contrast 1 (Pre 1 vs. Pre 2) | Contrast 2 (Post vs. Pre) |
|---|---|---|---|---|---|---|---|---|
| GABA+:H2O | 2.00 (0.33) | 1.81 (0.29) | 2.45 (0.53) | 2.50 (0.54) | 2.35 (0.37) |
F4,36 = 5.24,
P = 0.002 η2p = 0.37 |
F
1,9 = 2.56, P = 0.14 η2 p = 0.22 |
F1,9 = 25.18,
P = 0.001 η2p = 0.74 |
| GABA+:Cr | 0.121 (0.0160) | 0.111 (0.0197) | 0.144 (0.0353) | 0.147 (0.0356) | 0.138 (0.0168) |
F4,36 = 3.93,
P = 0.01 η2p = 0.30 |
F
1,9 = 1.52, P = 0.25 η2 p = 0.14 |
F1,9 = 16.72,
P = 0.003 η2p = 0.65 |
| Glx:H2O | 1.57 (0.25) | 1.62 (0.38) | 1.53 (0.40) | 1.50 (0.43) | 1.66 (0.36) |
F
4,36 = 0.50, P = 0.74 η2 p = 0.05 |
– | – |
| Glx:Cr | 0.094 (0.0180) | 0.098 (0.0223) | 0.088 (0.0214) | 0.085 (0.0200) | 0.095 (0.0179) |
F
4,36 = 0.90, P = 0.47 η2 p = 0.09 |
– | – |
| Cr FWHM (Hz) | 7.98 (0.60) | 7.93 (0.65) | 8.06 (0.56) | 7.85 (0.46) | 7.92 (0.40) |
F
4,36 = 0.44, P = 0.78 η2 p = 0.05 GGε = 0.28 |
– | – |
| Water frequency SD (Hz) | 0.62 (0.23) | 0.55 (0.19) | 0.49 (0.10) | 0.59 (0.13) | 0.60 (0.14) |
F
4,36 = 1.40, P = 0.25 η2 p = 0.14 |
– | – |
| Normalized fitting error E GABA,Water | 9.56 (2.57) | 9.67 (2.01) | 8.74 (2.16) | 10.03 (2.71) | 9.37 (1.99) |
F
4,36 = 0.53, P = 0.71 η2 p = 0.06 |
– | – |
Significant results are highlighted in bold. Planned comparisons were only carried out if a main effect was present in the rmANOVA. Data are reported as group mean (SD).