A, effect of the two‐pore domain K+ channel ligand halothane on the membrane current. B, effect of halothane on outward currents evoked by adenosine (100 μm), as measured at the time points a–c indicated in A. C, effect of bupivacaine on the outward current evoked by adenosine (100 μm). D, halothane and bupivacaine significantly reduced the adenosine‐evoked outward currents.