Table 5.
Per cent distribution of MyHC isoforms in the Control (Old_Ctrl) and Interventions (Old_Int) groups of older adults and Young subjects before bed rest, after bed rest and after physical retraining
| Old_Ctrl (n = 8) | Old_Int (n = 8) | Young (n = 7) | Significance | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pre‐BR | Post‐BR | R + 14 | Pre‐BR | Post‐BR | R + 14 | Pre‐BR | Post‐BR | R + 14 | Group | Time | G × T | |
| MyHC 1 | 47.4 ± 13.0 | 43.8 ± 10.8 | 44.0 ± 8.7 | 41.6 ± 7.7 | 41.8 ± 8.1 | 41.0 ± 9.7 | 35.7 ± 7.5 | 38.0 ± 8.4 | 35.9 ± 13.4 | 0.095 | 0.623 | 0.871 |
| MyHC 2A | 36.3 ± 10.2 | 35.0 ± 7.5 | 38.2 ± 16.5 | 37.1 ± 8.6 | 38.6 ± 9.1 | 40.3 ± 13.6 | 45.2 ± 13.5 | 48.3 ± 6.6 | 47.7 ± 12.3 | 0.084 | 0.536 | 0.921 |
| MyHC 2X | 15.8 ± 11.8 | 21.2 ± 9.3 | 17.1 ± 14.8 | 18.1 ± 11.2 | 19.6 ± 9.4 | 18.3 ± 15.9 | 19.1 ± 12.6 | 15.2 ± 8.8 | 16.4 ± 12.7 | 0.889 | 0.963 | 0.679 |
All values are means ± SD.
Pre‐BR: before bed rest; Post‐BR: after bed rest; R + 14: after physical retraining; F: peak force; v: peak velocity.
Significance by general linear model of the main effects of Group (Old_Ctrl vs. Old_Int vs. Young), Time (Pre‐BR vs. Post‐BR vs. R + 14) and Group × Time interaction (G × T).