Table 1. Morphometric data of HF and age-matched control rabbits.
Age-matched control | HF | |
---|---|---|
Age (years) | 2.40±0.17 | 2.46±0.35n.s. |
Body weight (kg) | 3.99±0.14 | 3.98±0.13n.s |
Heart weight (g) | 10.46±0.59 | 21.86±2.54*** |
HW/BW (g/kg) | 2.63±0.15 | 5.52±0.71** |
Lung weight (g) | 13.86±0.25 | 18.94±1.16** |
LW/BW (g/kg) | 3.49±0.12 | 4.95±0.21** |
LVESD (cm) | 1.08±0.07 | 1.63±0.11*** |
LVEDD (cm) | 1.71±0.07 | 2.29±0.09*** |
FS (%) | 36.70±2.02 | 28.39±1.13* |
All data represent mean±SEM. Unpaired, two-tailed Student’s t test;
p<0.05,
p<0.01,
p<0.001.
(HW/BW, heart weight–to–body weight ratio; LW/BW, lung weight–to–body weight ratio LVESD, left ventricular end-systolic diameter; LVEDD, left ventricular end-diastolic diameter; FS, fractional shortening calculated as FS=(LVEDD-LVESD)/LVEDD*100)