Table 4.
Overview of single-cell phylogenetic methods. Abbreviation: MCMC, Markov chain Monte Carlo.
Method | Phylogenetic representation | Inference |
---|---|---|
Kim and Simon [113] | Mutation tree | Pairwise ordering and maximum spanning tree |
BitPhylogeny [114] | Clonal tree | Tree-structure stick-breaking MCMC |
OncoNEM [115] | Sample/clonal tree | Greedy structure search |
SCITE [116] | Mutation treea | MCMC |
SCITE [116] provides the option of using the sample tree representation.