Table 3.

TEAEs in ≥20% of all treated patients

Preferred term	40-µg/kg dose (N = 18)		All treated patients (N=131)
	All grades	>Grade 3	All grades	>Grade 3
Any event	100	100	100	96
Febrile neutropenia	72	72	57	57
Fatigue	56	11	49	10
Thrombocytopenia	50	25	44	40
Anemia	22	42	38	33
Nausea	39	—	34	—
Diarrhea	17	—	31	2
Decreased appetite	22	6	30	2
Peripheral edema	28	—	30	2
Dyspnea	44	6	29	7
Constipation	33	—	25	—
Epistaxis	22	—	24	2
Hypokalemia	11	—	24	5
Cough	28	—	22	1
Chills	33	—	21	1
Contusion	39	—	21	—
Pyrexia	17	—	20	1
Neutropenia	28	28	18	19
Asthenia	22	18	18	—

Dashes indicate that toxicity did not occur at higher than Grade 3.