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. Author manuscript; available in PMC: 2018 Jun 18.
Published in final edited form as: Nat Struct Mol Biol. 2017 Dec 18;25(1):109–114. doi: 10.1038/s41594-017-0006-4

Figure 4. roX2 targets a subset of chromatin entry sites in females.

Figure 4

(a) roX2 is enriched on the X chromosome when expressed in female larvae. Data is plotted as fold enrichment over negative control. (b) roX2 occupancy is not enriched over most male binding sites. Data is plotted as the average log2 fold enrichment over the midpoint of each male peak. (c) Examples of female-bound chromatin entry sites. (d) Heatmap of roX2 occupancy on a subset of CES. Binding is abolished in msl-2 mutants 22. Data are represented as log2 transformed RNA-DamID signal. CES are k-means clustered according to roX2 signal in wild-type female larvae.